Panama · 5-star stays
Luxury hotels in Panama City
5-star hotels, boutique stays, and design-led properties in Panama City, Panama. The Expedia luxury collection — concierge service, spa access, and the city's best addresses, free cancellation on most rates.
- ✓5-star and boutique properties across Panama City
- ✓Spa, pool, and concierge service on most listings
- ✓The city's most-loved addresses, ranked by Panama City guest reviews
- ✓Free cancellation on most rates · Powered by Expedia